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Assalamallikum,

Today, 02Aug17, it was announced that teams from the Salk lnstitute, Oregon Health and Science University and Korea's lnsitute for Basic Science have used the molecular "scissors" CRISPR-Cas9 to replace a genetic mutation for a genetic heart condition. [The BBC reported that this gene is "known" for killing athletes at a young age.]  https://www.voanews.com/a/us-scientists-able-to-alter-genes-of-human-embryos-/3970001.html The result is that the defective mutation is eliminated both in the embryo and in future generations.

The publicized  "discussion" is about whether this is "gene editing" and "designing" --as in "designer babies".

So, what is your reaction?

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3 hours ago, hasanhh said:

The publicized  "discussion" is about whether this is "gene editing" and "designing" --as in "designer babies".

So, what is your reaction?

One should not alter their genes for verily Allah structured Man the way they are supposed to be. Allah creates us a certain way because its our destiny. Maybe this is an acceptable thing as long as major changes arent made to the genes.

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4 hours ago, hasanhh said:

Assalamallikum,

Today, 02Aug17, it was announced that teams from the Salk lnstitute, Oregon Health and Science University and Korea's lnsitute for Basic Science have used the molecular "scissors" CRISPR-Cas9 to replace a genetic mutation for a genetic heart condition. [The BBC reported that this gene is "known" for killing athletes at a young age.]  https://www.voanews.com/a/us-scientists-able-to-alter-genes-of-human-embryos-/3970001.html The result is that the defective mutation is eliminated both in the embryo and in future generations.

The publicized  "discussion" is about whether this is "gene editing" and "designing" --as in "designer babies".

So, what is your reaction?

Genes should be improved in case if babies have health issues and not to change them entirely. For example:- if it is ascertained that the coming baby is male trans-gender or female trans gender. The changes in genes are not wrong to take place to convert it into a healthy male or healthy female baby. Otherwise, it is haram as I have known previously from rulings of my marja. 

Edited by Sindbad05

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@hasanhh

Ahhh! You beat me to it, I was just about to post this. Very curious as to what the general consensus is on this topic. Islamically, that is. 

Were talking about a promise to access the direct source code of life......and from a scientific and ethical standpoint, it seems like a game of unintended consequences. At least thats what I've been reading.

An example, the elimination of mosquitoes, ergo, the end of malaria. But what about the bats that rely on mosquitoes for food? Then what? Habitat manipulation? Things can get really ugly, really fast.

 

And to all those preaching science!!!

 Slow ur roll, as with all things, human greed has found its way into CRISPR which has apparently been patented, locking in royalties worth billions, or potentially trillions depending on how crazy the scientific community gets with it. Money money money.

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18 hours ago, AfricanShia said:

One should not alter their genes for verily Allah structured Man the way they are supposed to be. Allah creates us a certain way because its our destiny. Maybe this is an acceptable thing as long as major changes arent made to the genes.

Your post prompted a search. l searched: "lslam + 'birth defects'"

lsamiCity.org  question #1499 dated 1997 cites a 1983 Kuwaiti Conference of scholars and doctors. Here abortion is permissible if the fetus is defective --but how 'late' had a variance of opinion. This also includes "late(r) in life" scenarios.

Another, focusing on KSA where opinions and decisions are based on how the 'problem' is parsed is here:  https://www.ncbi.nim.nih.gov/pmc/articles/PMC3761984/ 

So, as l personally question this, since abortion is permissible, later-in-life medical care is permissible, then pre-life medical care is also permissible.

@starlight l read 1st-cousin marriages are currently a contentious issue in Pakistan because of the number of birth defects created. So what is your thought?

 

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On 03/08/2017 at 6:29 AM, hasanhh said:

So, what is your reaction?

It's a stunning development. We have the ability to prolong life, prevent premature death and decrease human suffering due to death and disability. It is the future of medicine. 

As for designer babies, and picking blonde hair and blue eyes with superhuman strength for your offspring, there are correct and incorrect uses of everthing. People can get intoxicated by something as harmless as cough syrup. Doesn't mean you ban cough syrup. The more widespread use of CRISPR will depend on, among other things, effective legislation limiting its use for medicine. 

Surgeries are being performed in utero (eg: for spina bifida) and gene therapy is being used to treat genetic disease in children (eg: Duchenne and Becker muscular dystrophy) so I don't see why we can't start at conception. 

On 04/08/2017 at 4:35 AM, hasanhh said:

@starlight l read 1st-cousin marriages are currently a contentious issue in Pakistan because of the number of birth defects created. So what is your thought?

The cousin-marriage issue is blown out of proportion in Pakistan imho. It's not nearly as bad as people claim it is. The risk of congenital defects is only mildly higher in children of consanguinous parents. The vast majority of children of consanguineous parents are normal.  In many cultures and societies, cousin marriage might actually be beneficial. While I don't intend to promote cousin marriage, it's important to check your privelege and the reliable evidence available against cousin marriage before we start fear-mongering and schooling people about it.

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@Basim Ali l Iike your post. ^^^^

There is one popularized  item you posted l do not think is reliable: the preference for blond hair and blue eyes. This is not an attractive combination for most people --especially if the parents do not have them. l should note that l think this is true despite the fact that l personally do not like blonds.

Similarly, the "big blond [American] football player" falls into the same myth. How many people are going to spend Big Money to produce a 'dumb jock' that will acquire Chronic Traumatic Encephalopathy (CTE) --with acquired emotional problems and vegetating brain ?

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1 hour ago, hasanhh said:

@Basim Ali l Iike your post. ^^^^

There is one popularized  item you posted l do not think is reliable: the preference for blond hair and blue eyes. This is not an attractive combination for most people --especially if the parents do not have them. l should note that l think this is true despite the fact that l personally do not like blonds.

Similarly, the "big blond [American] football player" falls into the same myth. How many people are going to spend Big Money to produce a 'dumb jock' that will acquire Chronic Traumatic Encephalopathy (CTE) --with acquired emotional problems and vegetating brain ?

Thanks!

True, true. I only meant it figuratively like the descriptions in idioms that are used to show admiration/favoritism: 'his blue-eyed girl', 'their fair-haired boy' etc. 

Edited by Basim Ali

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